Laboratory Diagnosis and Surveillance of Thyroid Cancer

Thyroid carcinomas encompass a diverse group of malignancies with varying patient presentations, often featuring thyroid nodules. Diagnostic workup involves thyroid lab tests, imaging studies, and fine-needle aspiration. Treatment depends on carcinoma type, commonly involving surgical excision, radioactive iodine, or other modalities. Prognosis is generally favorable with high survival, necessitating long-term surveillance. Lab tests are crucial for monitoring treatment and possible disease recurrence. Thyroglobulin interpretation faces interferences; therefore, testing methods and optimal laboratory utilization are vital.

Originally published on March 28, 2024.

Lecture Presenter
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Adam Lyle, DO
Adam Lyle, DO
Pathology Resident, PGY 2, University of Utah School of Medicine

Dr. Adam Lyle earned his DO from Touro University California. Previously, he completed a BS in economics at Westminster College and had a career in finance.

Objectives

After this presentation, participants will be able to:

Explain the presentation, workup, treatment, and prognosis of thyroid carcinomas
Describe the laboratory tests used to monitor thyroid cancer treatment, recurrence, and the impact of certain autoantibodies on these assays
Compare and contrast thyroid cancer testing strategies and their implications for healthcare resources